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Autor:Van Rensburg, S.J.  
Título: Reproductive physiology and endocrinology of normal and habitually aborting Angora goats.
Idioma: EN
P.imprenta: 1971.
Serie:Onderstepoort Journal of Veterinary Research (South Africa). no. 38 p. 1-62.
Notas: Sum. (En)
Resumen: Recurrent abortion of non-infectious or non-organic origin is exceedingly prevalent in many species. In order to study the pathogenesis of this form of gestational failure, an experimental flock was constituted which consisted of normal and habitually aborting Angora goats, a species in which the high incidence of abortion constitutes a significant economic problem. Comparative studies on normal and aborting goats entailed: (i) Investigations of sexual behavioural patterns and of breeding performance in mature animals, followed by physiological, clinical and pathological observations on mature does, foetuses and kids. (ii) Development of suitable methods for the precise chemical assay of steroid hormone metabolism in goats. (iii) Investigation of the mohair growth rate as well as its fibre characteristics in relation to reproductive capabilities. (iv) Experimental reproduction in normal animals of the aberrations found and the investigation of the significance of such aberrations in causing gestation termination. Abortions were most frequent during the early part of the fourth month of gestation, a time which coincided with the most rapid increase in the rate of foetal growth and also with the cessation of placental growth. The condition of the foetus destined to be aborted suggested placental insufficiency; growth was retarded, anaemia was usually present and the concentration of some elements in the liver was abnormally low. The cause of abortion in Angora goats appears to be intimately related to a high metabolic priority for hair growth, artificially induced by intensive selection and inbreeding. An abnormally low level of adrenal function, coupled with some qualitative changes in adrenal steroid biosynthesis seems to be the responsible mechanism. Physiological adaptation involves adrenal hyperplasia in order to assist the transfer of maternal nutrients to the foetus. Abortion is a consequence of the failure of this mechanism

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